Lead Medical Safety Physician

For more than 25 years, Corcept has been singularly focused on the science of cortisol, a powerful hormone that when unregulated, can play a role in a broad range of diseases.

Our commercial portfolio includes treatments for hypercortisolism and oncology, and the company has discovered more than 1,000 proprietary selective cortisol modulators and glucocorticoid receptor antagonists. With advanced clinical trials in patients with hypercortisolism, solid tumors, ALS and liver disease, Corcept is unlocking the power of cortisol modulation to help address some of the most devastating diseases patients face today.

Corcept is headquartered in Redwood City, California. To learn more, visit www.corcept.com .

Reporting to the Vice President, Head of Patient Safety & Pharmacovigilance, this role will be responsible for leading the Medical Safety Physician function, ensuring the quality, consistency, and medical integrity of safety assessments across the portfolio. The individual will provide oversight of medical review, signal evaluation, and benefit–risk assessments across clinical development and post-marketing programs.

Operate as a peer functional leader alongside the Head of Safety Science, Head of Safety Operations, and QPPV(s) within the Patient Safety & Pharmacovigilance organization, partnering to provide strategic leadership, ensure effective governance, and maintain an integrated approach to patient safety and pharmacovigilance across the portfolio

Partner with key internal stakeholders, including Clinical Development and Medical Affairs to ensure alignment of safety insights across the product lifecycle while maintaining independent medical judgment on safety and benefit–risk decisions

Responsibilities

Medical Safety Leadership

Define and drive the medical safety strategy across the portfolio

Provide senior medical safety leadership for safety interpretation and benefit–risk assessment

Ensure consistent medical oversight of clinical and post-marketing safety activities

Team Leadership

Lead, build, and develop a team of Medical Safety Physicians

Set standards for medical review quality and consistency

Scale the organization to support portfolio and geographic growth

Safety Review & Surveillance

Lead medical evaluation of safety signals in partnership with Safety Science

Ensure robust benefit–risk assessment across programs

Integrate clinical interpretation into safety surveillance outputs

Key Collaboration

Partner with Clinical Development to integrate safety into development strategy

Partner with Medical Affairs to ensure consistent safety messaging

Provide medical interpretation and benefit–risk input to cross-functional decisions

Regulatory & Governance

Oversee medical input into DSURs, PADERs, and regulatory safety submissions

Support health authority interactions and safety queries

Contribute to cross-functional safety governance forums, providing medical expertise and benefit–risk input in cross-functional safety governance forums

Risk Management

Identify and escalate safety risks at product and portfolio level

Define medical risk mitigation strategies with cross-functional partners

Drive continuous improvement in medical safety processes and standards

Preferred Skills, Qualifications and Technical Proficiencies:

MD required; board certification in a relevant specialty strongly preferred

12+ years of progressive leadership experience in the pharmaceutical or biotechnology industry, including significant experience in Medical Safety and pharmacovigilance; oncology experience required

Demonstrated success leading Medical Safety organizations and managing teams of Medical Safety Physicians

Deep expertise in safety signal management, medical review, aggregate safety assessment, and benefit–risk evaluation across clinical development and post-marketing products

Extensive experience interacting with global health authorities and leading safety-related regulatory activities

Strong understanding of global pharmacovigilance regulations and industry best practices

Proven ability to influence cross-functional and executive-level decision-making and build effective partnerships across Patient Safety/Pharmacovigilance, Clinical Development, Regulatory Affairs, Medical Affairs and Biometrics

Experience building, scaling, or leading Medical Safety functions in fast-paced or growing organizations preferred

Preferred Education and Experience

Strategic medical leadership and executive presence

Clinical judgment and benefit–risk decision-making

Medical governance and patient safety leadership

Cross-functional influence and stakeholder management

Organizational leadership, talent development, and succession planning

Regulatory/ health authority engagement

Executive communication and presentation skills

Driving organizational change and continuous improvement

The pay range that the Company reasonably expects to pay for this headquarters-based position is $298,000 – $350,600; the pay ultimately offered may vary based on legitimate considerations, including geographic location, job-related knowledge, skills, experience, and education.

Applicants must be currently authorized to work in the United States on a full-time basis.

For information on how Corcept collects, uses, discloses, protects, and otherwise processes personal information and an explanation of the rights and choices available to you with respect to your personal information, please refer to our Privacy Notice link .

Corcept appreciates the commitment and hard work of all our team members as we strive to discover and develop novel treatments for patients with serious unmet medical needs.

Please visit our website at: https://www.corcept.com/

Corcept is an Equal Opportunity Employer

Corcept will not conduct interviews via text message or messaging platforms and will not ask you to download anything as part of your interview. Though we use third-party tools to help with advertising our jobs, please be vigilant in checking that the communication is in fact coming from Corcept.